Tchetverikov I et al. MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis. Ann Rheum Dis. 2005 May; 64(5): 694-698. Respectively, the ideal forms of both supplements are plant-based glucosamine sulfate 2KCl and CurcuWIN®, a premium, patented turmeric extract standardized to 20% curcuminoids and designed to make curcumin 46X more absorbable.

Acute nephrotoxicity (kidney injury) and high tacrolimus levels (29 nanogram/mL) were reported and attributed to turmeric in a person who had taken “15 or more spoonfuls” of turmeric powder daily for ten days before the high tacrolimus levels were recorded. The case report therefore describes evidence of turmeric moderately inhibiting CYP3A4. Hormone replacement therapy (HRT) Use caution when turmeric or curcumin are taken with medicines or supplements that have anticoagulant or antiplatelet (blood thinning) effects. Warfarin In an animal study, the amount of clopidogrel in the bloodstream was significantly increased when curcumin was taken at a high dose (100 mg/kg) for seven days. Turmeric helps improve blood flow to and from the heart, encouraging antiplatelet activity that can help prevent clogged arteries. Since it is rich in antioxidants, it helps manage cholesterol levels. It also eases any swelling in the heart and is good for the heart’s overall health. Curcumin may also help improve your memory and general brain health. Early studies suggest that regularly eating moderate amounts of curcumin can help increase brain chemicals that are linked to better memory formation and growth. Curcumin is also linked to a lower risk of dementia and Alzheimer’s disease .It has a strong anti-inflammatory effect (the strongest of all herbs, in my opinion). It’s more potent even than:

With Performance Lab® Flex , the best all-in-one joint support formula, the answer is no: you can enjoy the immense joint health benefits of both glucosamine and turmeric—and then some—without any issue.Glucosamine hydrochloride. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Oct. 24, 2020.

Besides this, glucosamine is less likely to be an effective treatment for other diseases or inflammatory conditions.Hui AY et al. A Systems Biology Approach to Synovial Joint Lubrication in Health, Injury, and Disease. Wiley Interdiscip Rev Sys Biol Med. 2012 Jan-Feb; 4(1): 15-37. However, make sure you get a product with at most 3 pills per day. Some require you to take up to 6, which is way too much. But for those of you who can’t tell the difference – it’s time to compare turmeric vs glucosamine supplements. ConsumerLab, NSF International, and US Pharmacopeia (USP) are a few independent companies that provide certification services. If you see one of their logos on your supplement, it’s more likely to be of good quality. Summary When taken in combination with these drugs, turmeric increases the body’s production of stomach acid. This may cause nausea, bloating and stomach pain, and damage to the esophagus.