In "No Way", Catherine of Aragon declares that, no matter what Henry does or says, she'll always be the true Queen of England.

Training from Hell: Anne Boleyn runs daily morning workouts for her fellow queens, where she shouts in their faces with a megaphone. The queens describe her as "intense". Visual Innuendo: After Anne Boleyn tells everyone that Henry "must've really liked her head" during "Don't Lose Ur Head", she positions her microphone near her mouth in a... suggestive fashion. The exact gesture varies between actresses, though. Girl Group: The entire concept of Six: the Musical. In-universe, each of the queens embarked on different music careers before being discovered and banded together by Catherine Parr. Her or me, feel note chum / Like I gotta be real note Don't wanna be some / I'm not a third wheel note girl in a threesome, are you blind?"Bittersweet Ending: The queens can't change history, or how their stories ultimately ended. Most of them were utterly miserable for most of the time they knew Henry, most of them met tragic ends, and they mostly became only known for who they are because of Henry or the children they had with him. However, they got a chance to tell their stories on their terms, retaking the narrative for a time. The show ends with them presenting a happier alternate world where most of them never married Henry (except for Jane Seymour, who stays with him and goes on to have more children) and wound up happier for it. During the West End cast change on 14 November 2021, every single solo was greeted with at least a minute of applause and cheering.

In 2019, the show opened on the West End at the aforementioned Arts Theatre and made its US debut at the Chicago Shakespeare Theater. Due to delays by the COVID-19 Pandemic, the musical debuted on Broadway October 3, 2021. The show has had numerous other productions since including numerous UK Tours, productions on the Norwegian Bliss and Norwegian Breakaway cruise ships, two Australian productions, two simultaneous US Tours, a South Korean production, non-replica Polish and Hungarian productions, and most recently, a Canadian production. Productions are currently being planned for China, Japan, and The Philippines.Abhorrent Admirer: Catherine Parr considers Henry this; she's already in love with another man and doesn't want to be forced to be with another just because he's the King. Rejected Marriage Proposal: In "Six", Catherine of Aragon's happy-ever-after involves her turning down her marriage with Henry VIII and voluntarily moving into a nunnery instead. Death by Childbirth: Jane Seymour's eventual fate. Though not covered in the musical, historically, Catherine Parr would die this way as well. Catherine Parr's solo fake-out used to be less elaborate. Instead of an entire musical sequence that could believably lead into an actual song, the band used to play a sparse, understated beat.